So Lot chose for himself the whole plain of the Jordan, and Lot journeyed eastward. Thus they parted from each other.
Rashi / classic midrash (eastward = away from God)
English: Lot journeyed from the east (mikedem) — he removed himself from the Ancient One of the world; he said: I want neither Avraham nor his God.
Supplementary classical material not listed by Torah Temimah under this exact passuk.